Will I build a tolerance to CBD?

Will I Build a Tolerance to CBD?

Dec 13, 2022Thomas K

There have been many studies done that show that CBD provides various therapeutic benefits. A person can take as low as 25 milligrams of CBD a day to almost 3,000 milligrams, as per the FDA approved CBD medication used to treat epileptic seizures. CBD oil tinctures, along with edibles, have been proven to be safe across this wide range, which in turn made them a common treatment option when compared to plan old pharmaceuticals.

Many people know the benefits of CBD, but then the question comes up: Will I build a tolerance to CBD?

How Does CBD Tolerance Work?

   When you look at different CBD products, there will a varying serving size that are required for a desired outcome. One thing to keep in mind is that the endocannabinoid tone has a major role in determining how large of a serving size is needed.

   The endocannabinoid tone describes the unique make up of a person’s endocannabinoid system (ECS) and they are:

  • Level of endocannabinoids
  • Activity of enzymes that produce and break down the above
  • The number of endocannabinoid receptors

The many cannabinoids in CBD act the same way THC does in the body: interacting with ECS system. The system is flexible and will react differently when various concentrations of cannabinoids enter the body.  

If I Take Too Much CBD: Will I Build a Tolerance to It?

The simple answer is: No.

   The main reason why our bodies do not gain a tolerance is because CBD does not bind the CB1 receptors the same way. Once CBD binds with the CB1 Receptors they do not be desensitized.

   There has been research done that states that in a  2011 study published by Mateus Machodo Bergamaschi found that “CBD administration did not induce side effects across a wide range of dosages, including acute and chronic dose regimens, and tolerance to CBD did not develop "

   If you do feel that you are building a tolerance, because everyone is unique, take a “tolerance break”. This break can be up to a week long, and then slowly build back your milligrams to the dosage you were at before.

   The bottom line is that you most likely will not build a tolerance to the benefits of CBD. If the current serving sizes are working for you, there is no need to switch. Keep it simple and stay gritty.

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